At the heart of our mission is a commitment to innovation and improving healthcare outcomes through the advancement of medical knowledge. From day one, we’ve focused on delivering high-quality research that makes a real difference to patients and the communities we serve.

Participating In A Research Study

If you’re registered with one of our practices, you may be invited by phone, email, or letter to take part in a research study.

Taking part is entirely voluntary, and there’s no obligation to participate.

Received An Invitation?

If you’ve received an invitation and would like to know more about the study – or if you’re simply interested in our research – please contact our dedicated team for Leicestershire or Warwickshire. They’ll be happy to provide more details and answer any questions about our current studies.

OPTIMISE 2

Leicestershire & Warwickshire Practices

Nuffield Department of Primary Care Health Sciences
University of Oxford

Optimise 2 is a national trial exploring whether it’s safe to reduce or stop blood pressure medication in people aged 75 and over who no longer have high blood pressure. By carefully “deprescribing” in a controlled way, the study aims to show that older adults can remain healthy while taking fewer medicines.

CORAL

Leicestershire Practices

Coenzyme Q10 in heart failure

The CORAL study involves adults with heart failure with reduced ejection fraction who take either CoQ10 or a placebo capsule three times a day for 12 months. The study aims to assess whether CoQ10 can improve symptoms and overall quality of life.

The PAPER Study

Leicestershire Practices

Prescribing Antidepressants in Primary care: Ethnic inequalities in tReatment
University of Surrey

Prescribing antidepressants can be complicated, especially in communities where culture, language, or stigma make it harder to talk about mental health. The PAPER study is listening to South Asian patients recently diagnosed with depression, through interviews and group discussions, to understand how antidepressants are prescribed and how people feel about their treatment.

DAPPLE Project

Leicestershire Practices

End of life care for People with a learning disability.

People with learning disabilities often face barriers to receiving good end-of-life care. The DAPPLE Project is spending time with people receiving palliative or end-of-life care, their families, and the professionals supporting them to understand their experiences and explore how well their voices are heard.

SNIFF

Warwickshire Practices

Determinants of Disease Severity in Influenza Infection
St. Jude Care & Treatment

The SNIFF (Sniff) study is a Phase 2 clinical trial testing a nasal spray flu vaccine in children aged 12–23 months. The research aims to understand why some children and young people become seriously ill with flu while others only get mild symptoms.

DaRe2THINK

Warwickshire Practices

DaRe2THINK Trial

DaRe2THINK is an NHS-based research study for people with atrial fibrillation (AF). It’s exploring whether starting blood-thinning treatment earlier can help prevent stroke, memory problems, and other vascular conditions compared with current standard care.